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✨ Wake up to radiant, resilient skin—no retinol drama needed!
Cetaphil Healthy Renew Skin Tightening Night Cream is a dermatologist-developed, fragrance-free formula designed for sensitive skin. It uses purified peptides as a gentle retinol alternative to visibly reduce fine lines and wrinkles within 2 weeks, while providing up to 48 hours of hydration. Enriched with Vitamins B3 and B5, it supports skin barrier repair and targets dullness and uneven tone. Hypoallergenic and paraben-free, this night cream delivers effective anti-aging benefits without irritation, making it ideal for consistent nightly use.









| ASIN | B0C15N3473 |
| ASIN | B0C15N3473 |
| Active Ingredients | peptides,retinol |
| Age Range Description | Adult |
| Best Sellers Rank | #4,535 in Beauty & Personal Care ( See Top 100 in Beauty & Personal Care ) #133 in Face Moisturizers |
| Brand Name | Cetaphil |
| Customer Reviews | 4.4 4.4 out of 5 stars (1,954) |
| Global Trade Identification Number | 00302990260014 |
| Item Dimensions | 5.91 x 2.76 x 5.91 inches |
| Item Form | Cream |
| Item Volume | 1.7 Fluid Ounces |
| Item Weight | 5.6 ounces |
| Item model number | 0299.026001 |
| Manufacturer | Galderma |
| Manufacturer | Galderma |
| Manufacturer Part Number | 0299.026001 |
| Material Features | Natural |
| Material Type Free | Paraben Free |
| Model Name | Night Cream |
| Model Number | 0299.026001 |
| Number of Items | 1 |
| Other Special Features of the Product | Anti Aging |
| Product Benefits | Anti-Aging, Even Toning, Hydrating, Soothing |
| Product Dimensions | 5.91 x 2.76 x 5.91 inches; 5.6 ounces |
| Recommended Uses For Product | Anti-Aging, Dryness, Sensitive Skin, Uneven Skin Tone, Wrinkles |
| Scent Name | Unscented |
| Skin Type | Sensitive |
| Special Ingredients | retinol |
| Specific Uses For Product | Dryness, Uneven Skin Tone, Wrinkles |
| Target Use Body Part | Face |
| UPC | 302990260014 |
| UPC | 302990260014 |
| Unit Count | 1.7 Ounce |
J**N
Excellent retinol alternative - real improvements in texture and fine lines after a year
I’ve been using the entire Cetaphil Healthy Renew line for over a year now, and this night cream has become an essential part of my routine. As someone who can’t tolerate retinol, I was looking for an effective alternative that would help with aging skin concerns without the irritation. Results I’ve seen: After consistent use over the past year, I’ve noticed genuine improvements in both my skin texture and fine lines. My skin feels smoother and looks more refined, and the fine lines around my eyes and forehead are visibly reduced. These aren’t overnight results - it took a few months to really see the difference - but the improvements have been steady and lasting. What I appreciate about this cream: The formula is gentle enough for nightly use without any of the sensitivity, redness, or peeling I experienced when I tried retinol products in the past. It absorbs well without feeling heavy or greasy, which is important for a night cream since I don’t want it transferring to my pillowcase. The texture is rich but not overly thick. A little goes a long way, so the jar lasts longer than I initially expected. It layers nicely with the other products in the Healthy Renew line. Worth noting: This is a commitment product - you need patience and consistency to see results. If you’re looking for dramatic overnight changes, this isn’t it. But if you want steady, sustainable improvement in skin texture and fine lines without harsh active ingredients, it delivers. The jar packaging isn’t the most hygienic compared to a pump, though I use a small spatula to keep things clean. Bottom line: For anyone who can’t use retinol but still wants anti-aging benefits, this night cream is worth trying. After a year of use, I can confidently say it’s made a real difference in my skin’s appearance and texture. I’ll continue repurchasing this and using it as part of my nighttime routine.
M**V
High quality moisture suitable for sensitive skin for a great price
Surprisingly amazing night cream at a bargain. My skin has never been so happy. The only downside is that it smells kinda weird.
L**O
Very moisturizing
Just as described on the website and it arrived quickly. Very creamy and works great. Very nice on sensitive skin.
Q**E
Good product with odd odor
Texture is nice, but I find the odor a bit off putting. I think it's a good product but not my favorite.
K**R
Holy Grail product. Highly recommend
I was gifted an extremely expensive facial treatment at a very high end spa recently. At the end of this treatment, I quizzed the esthetician about a routine and products to maintain my skin post-treatment. I expected she would give me a list of products sold in the spa, but she told me to skip them all in favor of mixing my favorite serum with Cetaphil Healthy Renew and slathering my face with it nightly. I’ve been doing this for two months, and my skin has never looked better. I’m over 60 and have dry skin, so that’s a huge deal to me. And the price doesn’t hurt! I’ve used a LOT of expensive creams in my search for the holy grail skincare product, but none of them have provided the results that this does.
N**Y
Cetaphil Healthy Renew Skin Tightening Night Cream: A Gentle Yet Effective Anti-Aging Solution
I recently incorporated Cetaphil Healthy Renew Skin Tightening Night Cream into my skincare routine, and I am thrilled with the results. As someone with sensitive skin, I've always been cautious when it comes to anti-aging products. However, this night cream has proven to be a gentle yet highly effective solution. The standout feature of this night cream is its formula enriched with peptides, providing an excellent alternative to traditional retinol creams. Peptides are known for their ability to stimulate collagen production, which is essential for maintaining youthful and firm skin. This cream harnesses the power of peptides without the potential irritation that can come with retinol-based products. One of the first things I noticed after using this night cream consistently is the visible reduction in the appearance of fine lines and wrinkles. My skin feels smoother and firmer, and the results have been noticeable within just a few weeks of use. It's reassuring to know that I can achieve these benefits without subjecting my sensitive skin to harsh treatments. The texture of the cream is luxurious and hydrating, and it absorbs quickly into the skin without leaving a heavy or greasy residue. I appreciate that it doesn't cause any redness or irritation, even when used nightly. It's a comforting feeling to wake up with refreshed and rejuvenated skin every morning. Cetaphil has once again impressed me with their commitment to creating products specifically designed for sensitive skin. This night cream is hypoallergenic, which gives me peace of mind knowing that I won't experience any adverse reactions. It's also fragrance-free, which is another bonus for those of us with sensitive skin.
A**R
Very good
Good product daughter and wife used it all the time
J**M
Not completely fragrance free. A light fragrance might actually help me feel better about using it.
I bought this night cream to try to replace a much more expensive cream I've been using for years, however I am spoiled by the nice, light scent of the more expensive brand. The Cetaphil might work fine, but if you have a sensitive nose like I do, the scent might turn you off. It's supposed to be fragrance free, but it smells a bit like plastic to me.
E**Z
Es muy buena crema, suaviza y nutre. La cara, no tiene buen olor, pero cumple con mantener la piel hidratada.
K**A
Product was very smelly and I wasn’t able to use it.
E**A
Buen producto
K**A
llego bien pero aun no se si funciona del todo, espero que pase el tiempo para saberlo
A**A
Me gusta como deja mi piel seguí la recomendación a través de Instagram y de verda que es buena
Trustpilot
3 days ago
5 days ago