---
product_id: 3999959
title: "Nutramax Laboratories Denosyl Liver and Brain Health Supplement for Large Dogs, With S-Adenosylmethionine (SAMe), 30 Tablets"
brand: "nutramax laboratories"
price: "€ 81.92"
currency: EUR
in_stock: true
reviews_count: 12
category: "Nutramax Laboratories"
url: https://www.desertcart.fr/products/3999959-nutramax-laboratories-denosyl-liver-and-brain-health-supplement-for-large
store_origin: FR
region: France
---

# supports cognitive function 425mg bioavailable SAMe boosts glutathione detox Nutramax Laboratories Denosyl Liver and Brain Health Supplement for Large Dogs, With S-Adenosylmethionine (SAMe), 30 Tablets

**Brand:** nutramax laboratories
**Price:** € 81.92
**Availability:** ✅ In Stock

## Summary

> 🐾 Elevate your dog’s vitality — because their health deserves the best!

## Quick Answers

- **What is this?** Nutramax Laboratories Denosyl Liver and Brain Health Supplement for Large Dogs, With S-Adenosylmethionine (SAMe), 30 Tablets by nutramax laboratories
- **How much does it cost?** € 81.92 with free shipping
- **Is it available?** Yes, in stock and ready to ship
- **Where can I buy it?** [www.desertcart.fr](https://www.desertcart.fr/products/3999959-nutramax-laboratories-denosyl-liver-and-brain-health-supplement-for-large)

## Best For

- nutramax laboratories enthusiasts

## Why This Product

- Trusted nutramax laboratories brand quality
- Free international shipping included
- Worldwide delivery with tracking
- 15-day hassle-free returns

## Key Features

- • **Tailored for Large Dogs:** Precise dosing for dogs 35+ lbs, supporting liver and brain health at every life stage.
- • **Veterinarian Trusted Brand:** From Nutramax, the #1 vet-recommended supplement company with 30+ years of pet health expertise.
- • **Optimized Absorption Formula:** Enteric-coated tablets ensure maximum bioavailability when given on an empty stomach.
- • **Clinically Proven Liver Detox:** 425mg of bioavailable SAMe enhances your dog’s natural glutathione levels for powerful liver support.
- • **Neuroprotective Cognitive Boost:** Scientifically backed SAMe helps maintain sharpness and reduce anxiety in aging large dogs.

## Overview

Denosyl Liver and Brain Health Supplement delivers 425mg of bioavailable S-Adenosylmethionine (SAMe) per tablet, scientifically formulated to boost liver detoxification and cognitive function in large dogs. Trusted by veterinarians for over 30 years, this enteric-coated supplement ensures optimal absorption and supports your dog’s wellness from liver health to mental sharpness.

## Description

Denosyl contains SAMe (s-adenosylmethionine) to help support the liver health of dogs and may support brain health. It is available in enteric-coated tablets. Denosyl Liver Health Supplements are brought to you by Nutramax Laboratories Veterinary Sciences, the #1 veterinarian recommended supplement company. *Source: Survey conducted among small animal veterinarians who recommended animal supplements.

Review: Please buy this for your dog! Great for Cognitive issues and liver! - Currently waiting on 2 more packs of these! I ran out 2 days ago and my girl is getting anxious again. She has slightly elevated liver enzymes but I started her on this for cognitive issues. She is still listening to commands and doesn't get lost but her night time anxiety and barking has increased now that she is almost 11. This girl has been through everything medically. Her bloodwork, urine and stool samples are all flawless other than the slight elevated liver levels. We have been fighting symptoms for 2 months and THIS supplement got her back to 100%. She is seriously so sharp now! I will keep her on these for life. Just seeing what day 2 without them is like. She's not bad, but her normal routine is being disturbed by her barking and pacing. It should be here within an hour. I almost guarantee she will be back to normal by tomorrow. I gave her all her meds (even extra cbd). The only thing she has missed is this med and she is more irritable/anxious. I seriously can't wait to get these in. I give them afternoon after we get home from work, on an empty stomach and 2 hours before dinner. She is on a probiotic and pumpkin, so no stomach upset. Put it in a pill pocket if they wont take it! Once it started helping her, she takes it with no problem. She wants to take it! Thank you for making a supplement that WORKS!
Review: Great price - Cheaper here then from the Vet, my pup takes these daily

## Features

- Liver Support: Denosyl features s-adenosylmethionine (SAMe) to support the liver by increasing levels of glutathione, an important antioxidant for liver health and the liver's main detoxifier
- Bioavailability: The SAMe in Denosyl has been proven to be bioavailable, meaning it enters your pet's bloodstream to help support the liver
- Cognitive Support: Research has shown that SAMe may also support cognitive function in dogs and act as a neuroprotector
- From the #1 Veterinarian Recommended Supplement Company*: Nutramax Laboratories Veterinary Sciences has been a leader in pet health for over 30 years, and provides supplements to support joint health, digestive health, and overall wellness
- Backed by Science: Nutramax Laboratories Veterinary Sciences supplements are veterinarian formulated with high-quality ingredients to ensure your pet is receiving a safe supplement

## Technical Specifications

| Specification | Value |
|---------------|-------|
| ASIN | B000RI3N1S |
| ASIN  | B000RI3N1S |
| Age Range Description | All Life Stages |
| Best Sellers Rank | #12,240 in Pet Supplies ( See Top 100 in Pet Supplies ) #240 in Dog Hip & Joint Care |
| Brand Name | Nutramax Laboratories |
| Breed Recommendation | Large |
| Color | White |
| Country of Origin | United States |
| Customer Reviews | 4.6 4.6 out of 5 stars (1,089) |
| Date First Available | December 21, 2007 |
| Date First Available  | December 21, 2007 |
| Directions | For dogs 35 - 65 lbs, 1 tablet per day, for dogs 66 - 120 lbs, 2 tablets per day, and for dogs over 120 lbs, 3 tablets per day. Tablets should be given on an empty stomach for optimal absorption. They may be given at least two hours after a meal or one hour before a meal. |
| Included Components | 30 doses |
| Is Discontinued By Manufacturer  | No |
| Item Dimensions LxWxH | 5.75 x 1.2 x 3.75 inches |
| Item Package Dimensions L x W x H | 5.71 x 3.58 x 1.46 inches |
| Item Weight | 1.6 Ounces |
| Item model number | DENO425MG |
| Item model number  | DENO425MG |
| Manufacturer | Nutramax |
| Manufacturer  | Nutramax |
| Model Name | Nutramax Denosyl Tablets 30 ct |
| Number of Items | 30 |
| Product Dimensions  | 5.75 x 1.2 x 3.75 inches; 1.6 ounces |
| Size | Large Dog (Over 35 lbs) |
| Specific Uses for Product | Urinary |
| Target Audience Keyword | ( reptiles | amphibians ), dogs |

## Product Details

- **Active Ingredients:** S-Adenosylmethionine 425 mg
- **Brand:** Nutramax Laboratories
- **Flavor:** Other
- **Item Form:** Tablet
- **Item Weight:** 1.6 Ounces

## Images

![Nutramax Laboratories Denosyl Liver and Brain Health Supplement for Large Dogs, With S-Adenosylmethionine (SAMe), 30 Tablets - Image 1](https://m.media-amazon.com/images/I/61+UqXybZML.jpg)
![Nutramax Laboratories Denosyl Liver and Brain Health Supplement for Large Dogs, With S-Adenosylmethionine (SAMe), 30 Tablets - Image 2](https://m.media-amazon.com/images/I/61MM2OQOz6L.jpg)
![Nutramax Laboratories Denosyl Liver and Brain Health Supplement for Large Dogs, With S-Adenosylmethionine (SAMe), 30 Tablets - Image 3](https://m.media-amazon.com/images/I/61N9QfiYHuL.jpg)
![Nutramax Laboratories Denosyl Liver and Brain Health Supplement for Large Dogs, With S-Adenosylmethionine (SAMe), 30 Tablets - Image 4](https://m.media-amazon.com/images/I/81CnYSEAiYL.jpg)
![Nutramax Laboratories Denosyl Liver and Brain Health Supplement for Large Dogs, With S-Adenosylmethionine (SAMe), 30 Tablets - Image 5](https://m.media-amazon.com/images/I/81FQ816n2cL.jpg)

## Customer Reviews

### ⭐⭐⭐⭐⭐ Please buy this for your dog! Great for Cognitive issues and liver!
*by A***R on December 28, 2025*

Currently waiting on 2 more packs of these! I ran out 2 days ago and my girl is getting anxious again. She has slightly elevated liver enzymes but I started her on this for cognitive issues. She is still listening to commands and doesn't get lost but her night time anxiety and barking has increased now that she is almost 11. This girl has been through everything medically. Her bloodwork, urine and stool samples are all flawless other than the slight elevated liver levels. We have been fighting symptoms for 2 months and THIS supplement got her back to 100%. She is seriously so sharp now! I will keep her on these for life. Just seeing what day 2 without them is like. She's not bad, but her normal routine is being disturbed by her barking and pacing. It should be here within an hour. I almost guarantee she will be back to normal by tomorrow. I gave her all her meds (even extra cbd). The only thing she has missed is this med and she is more irritable/anxious. I seriously can't wait to get these in. I give them afternoon after we get home from work, on an empty stomach and 2 hours before dinner. She is on a probiotic and pumpkin, so no stomach upset. Put it in a pill pocket if they wont take it! Once it started helping her, she takes it with no problem. She wants to take it! Thank you for making a supplement that WORKS!

### ⭐⭐⭐⭐⭐ Great price
*by J***Y on July 8, 2025*

Cheaper here then from the Vet, my pup takes these daily

### ⭐⭐⭐⭐⭐ If her levels had been higher I would have given it to her every day like recommended. The vet told me that the Denosyl ...
*by J***N on December 26, 2016*

I have a 12 year old Siberian Husky. Ever since she was about 6 years old, I have had a full blood panel run on her once a year. This past June for the first time ever she had a slightly elevated liver level. It was 198. The year before it was 155. The vet wasn't too concerned as it was only slightly elevated. He said that I could start giving her Denosyl. The price at the vet was $85.00 for 30 pills. I fount it here on Amazon for $50. I started giving it to here in July or August. I have been giving it to for about 4 months. I probably give it to her about 4 days a week. Since her levels were only slightly elevated I figured it was okay if I missed a few days a week. I also give her Metacam daily for arthritis that she has had since she was a puppy. I have 4 Siberian Huskies and it obviously gets expensive caring for all of them, so it saves a little money not giving it to her everyday. I took her this week to have another blood panel run. It has been 6 months since the last blood work in June 2016. Her Liver level dropped from 198 to 142! It is now lower than it was a year and half ago when I tested her in June 2015 and it was 155 and was still considered normal. I am thrilled with the results of this in only 4 months giving it to her everyother day. If her levels had been higher I would have given it to her every day like recommended. The vet told me that the Denosyl must be working and that I can still give it to her everyother day if I would like. I will definitely continue giving this product to my dog. I am thrilled with the results in just 4 short months.

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*Product available on Desertcart France*
*Store origin: FR*
*Last updated: 2026-01-24*