---
product_id: 3791305
title: "Nature Made SAM-e Complete 400 mg, SAM-e Supplement for Mood Support, Dietary Supplement, 36 Tablets, 36 Day Supply"
brand: "nature made"
price: "€ 63.12"
currency: EUR
in_stock: true
reviews_count: 7
category: "Nature Made"
url: https://www.desertcart.fr/products/3791305-nature-made-sam-e-complete-400-mg-sam-e-supplement
store_origin: FR
region: France
---

# 36-day supply, daily routine ready 400 mg potent SAM-e dose Supports joint comfort with sulfur Nature Made SAM-e Complete 400 mg, SAM-e Supplement for Mood Support, Dietary Supplement, 36 Tablets, 36 Day Supply

**Brand:** nature made
**Price:** € 63.12
**Availability:** ✅ In Stock

## Summary

> ✨ Elevate your mood and move freely — the smart supplement for the mindful millennial 💼

## Quick Answers

- **What is this?** Nature Made SAM-e Complete 400 mg, SAM-e Supplement for Mood Support, Dietary Supplement, 36 Tablets, 36 Day Supply by nature made
- **How much does it cost?** € 63.12 with free shipping
- **Is it available?** Yes, in stock and ready to ship
- **Where can I buy it?** [www.desertcart.fr](https://www.desertcart.fr/products/3791305-nature-made-sam-e-complete-400-mg-sam-e-supplement)

## Best For

- nature made enthusiasts

## Why This Product

- Trusted nature made brand quality
- Free international shipping included
- Worldwide delivery with tracking
- 15-day hassle-free returns

## Key Features

- • **Joint Comfort Support:** Sulfur-enriched formula to ease joint discomfort naturally
- • **Easy Daily Integration:** One tablet daily on an empty stomach fits seamlessly into busy lifestyles
- • **Clean & Pure Ingredients:** Gluten-free, no artificial flavors or preservatives for mindful wellness
- • **Mood & Emotional Balance Boost:** Clinically supported SAM-e to elevate mood in 7-14 days
- • **Trusted Pharmacist Recommended Brand:** #1 choice for quality and reliability in supplements

## Overview

Nature Made SAM-e Complete delivers a potent 400 mg dose of SAM-e, a natural molecule that supports healthy mood and joint comfort. This gluten-free, preservative-free supplement is designed for adults seeking a trusted, pharmacist-recommended formula to enhance emotional wellbeing and joint health with daily use over a 36-day supply.

## Description

Product Description Nature Made SAM-e Complete(1) 400 mg Tablets are dietary mood supplements that help support a healthy mood in as little as 7 to 14 days when taken daily. Sourced from high-quality ingredients, these gluten-free tablets contain no artificial flavors and no preservatives. SAM-e (S-adenosylmethionine) is a naturally occurring molecule produced by the body that can run low due to factors such as a poor diet and aging. These SAM-e supplements are a great choice for adults who are looking to replenish their SAM-e levels. This SAMe 400mg supplement delivers a 400 mg dose that also supplies sulfur, a critical component of joint tissue, to help support joint comfort. Nature Made SAM-e Complete(1) is made for adults to take by mouth with water at home or on the go and fits perfectly into any supplement user’s routine. Nature Made supplements, including this SAMe supplement, are quality you can trust. (1)Complete because studies have shown that SAM-e helps support a healthy mood & joint comfort. *Based on a survey of pharmacists who recommend branded vitamins and supplements. Brand Story By Nature Made

Review: Very high quality SAM-e, possibly the best in the market. - I have an injury to my right hip joint. A small piece of bone is in my joint. There was a 50% chance that surgery would make it worse, so I didn't have a hip surgery. I heard someone praise SAM-e on Doctor Radio, so I bought the enterically coated brand that was mentioned along with some others. Nature Made SAM-e has stopped the pain. I take 2 of the tablets for best effectiveness. Studies have shown that joint comfort from SAM-e supplementation is best achieved at 600 to 1200 mgs. I don't use it for mood support which by the way would need a higher dose. I tried another brand that was on sale at desertcart, but after a month my hip pain was insufferable and had to take Aleve to do simple tasks. I started taking this brand of SAM-e again and in a few days the pain was gone so I didn't need Aleve.
Review: The Best SAM-e - Nature Made is the best SAM-e. Can never find it in Walgreens or Rite Aid anymore. Sucks because it was the only way it was affordable when it would be bogo. They don’t even sell the Walgreens or Rite Aid brands anymore I don’t get it. I bought naturemade religiously for over 20 years. I can’t afford it at this price but as long as the expiration date is like 2 years out and it’s fresh, they always made the best one. Enteric coated, empty stomach with B12, B6 & Folic acid. 1200-1600 mg a day for mood. 400-800 for joints and liver detoxification. Miracle supplement.

## Features

- Mood support supplement: contains one 36 count carton of Nature Made Complete(1) SAM-e 400mg Tablets
- Nature Made SAM-e 400mg mood supplement provides SAM-e to help support a healthy mood and emotional wellbeing
- SAM e 400mg is also a joint health supplement, providing a source of sulfur to help support joint comfort
- Adults, start by taking one SAM e supplement tablet daily with water on an empty stomach as part of a daily routine
- Sourced from high-quality ingredients, each Nature Made SAM-e tablet is gluten-free and contains no artificial flavors and no preservatives
- #1 Pharmacist Recommended Vitamin & Supplement Brand*
- These statements have not been evaluated by the Food and Drug Administration; this product is not intended to diagnose, treat, cure, or prevent any disease

## Technical Specifications

| Specification | Value |
|---------------|-------|
| ASIN  | B0002D150Y |
| Best Sellers Rank | #14,431 in Health & Household ( See Top 100 in Health & Household ) #386 in Blended Vitamin & Mineral Supplements |
| Customer Reviews | 4.5 4.5 out of 5 stars (3,166) |
| Date First Available  | April 15, 2004 |
| Is Discontinued By Manufacturer  | No |
| Item model number  | 1107Z |
| Manufacturer  | Pharmavite |
| Product Dimensions  | 2.25 x 3.13 x 5.13 inches; 2.39 ounces |

## Product Details

- **Age Range (Description):** Adult
- **Brand:** Nature Made
- **Diet Type:** Gluten Free
- **Flavor:** Unflavored
- **Item Form:** Tablet
- **Item Weight:** 2.39 Ounces
- **Item dimensions L x W x H:** 2.25 x 3.13 x 5.13 inches
- **Primary Supplement Type:** SAM-e
- **Product Benefits:** Bone & Joint Support
- **Unit Count:** 36 Count

## Images

![Nature Made SAM-e Complete 400 mg, SAM-e Supplement for Mood Support, Dietary Supplement, 36 Tablets, 36 Day Supply - Image 1](https://m.media-amazon.com/images/I/71ZmieYOG7L.jpg)
![Nature Made SAM-e Complete 400 mg, SAM-e Supplement for Mood Support, Dietary Supplement, 36 Tablets, 36 Day Supply - Image 2](https://m.media-amazon.com/images/I/71SkU5r4luL.jpg)
![Nature Made SAM-e Complete 400 mg, SAM-e Supplement for Mood Support, Dietary Supplement, 36 Tablets, 36 Day Supply - Image 3](https://m.media-amazon.com/images/I/910QJojwDoL.jpg)
![Nature Made SAM-e Complete 400 mg, SAM-e Supplement for Mood Support, Dietary Supplement, 36 Tablets, 36 Day Supply - Image 4](https://m.media-amazon.com/images/I/71lW08NZNWL.jpg)
![Nature Made SAM-e Complete 400 mg, SAM-e Supplement for Mood Support, Dietary Supplement, 36 Tablets, 36 Day Supply - Image 5](https://m.media-amazon.com/images/I/71gb2BWGSGL.jpg)

## Available Options

This product comes in different **Size** options.

## Questions & Answers

**Q: does this product have mannitol in it?**
A: Yes but it is ingredient #10 out if 14.

**Q: What's the difference between Sam-e and Sam-e complete?**
A: Nature Made calls theirs complete but if the active ingredient is S-adenosylmethionine , I don't think there is a difference. They used to call it Sam-e Mood something or other but now it's "complete". Not sure why. Sam-e refers to the abbreviation of S-adenosylmethionine only.

**Q: How long does it take before you feel the effects of taking sam-e? thanks**
A: You start feeling better within an hour

**Q: Are they butanedisulfonate form in enteric-coated tablets??**
A: Mine says S-adenosylmethionine enteric coated.  I can't find the chemical term anywhere on the box you asked about.

## Customer Reviews

### ⭐⭐⭐⭐⭐ Very high quality SAM-e, possibly the best in the market.
*by R***E on September 14, 2025*

I have an injury to my right hip joint. A small piece of bone is in my joint. There was a 50% chance that surgery would make it worse, so I didn't have a hip surgery. I heard someone praise SAM-e on Doctor Radio, so I bought the enterically coated brand that was mentioned along with some others. Nature Made SAM-e has stopped the pain. I take 2 of the tablets for best effectiveness. Studies have shown that joint comfort from SAM-e supplementation is best achieved at 600 to 1200 mgs. I don't use it for mood support which by the way would need a higher dose. I tried another brand that was on sale at Amazon, but after a month my hip pain was insufferable and had to take Aleve to do simple tasks. I started taking this brand of SAM-e again and in a few days the pain was gone so I didn't need Aleve.

### ⭐⭐⭐⭐⭐ The Best SAM-e
*by J***N on June 7, 2025*

Nature Made is the best SAM-e. Can never find it in Walgreens or Rite Aid anymore. Sucks because it was the only way it was affordable when it would be bogo. They don’t even sell the Walgreens or Rite Aid brands anymore I don’t get it. I bought naturemade religiously for over 20 years. I can’t afford it at this price but as long as the expiration date is like 2 years out and it’s fresh, they always made the best one. Enteric coated, empty stomach with B12, B6 & Folic acid. 1200-1600 mg a day for mood. 400-800 for joints and liver detoxification. Miracle supplement.

### ⭐⭐⭐⭐⭐ It helps. A lot.
*by S***H on July 21, 2025*

Easy to take . More energy. Less depression. I stopped taking my Rx over time .. slowly. As it was making me feel sick. I tried this 30 days ago and this is my 2nd box. I feel the difference right away. Take first thing in the morning, empty stomach. I think if this is available I will use the rest of my life. Feel more positive. Helps my anxiety and my joints. I'm thankful.

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*Product available on Desertcart France*
*Store origin: FR*
*Last updated: 2026-03-03*