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🐾 Stay ahead of fleas—because your big cat deserves big protection!
Advantage Bayer II Flea Prevention for Large Cats (over 9 lbs) delivers fast-acting, vet-recommended flea control that kills fleas through contact within 12 hours and protects for 30 days. Its waterproof, fragrance-free formula targets all flea life stages—eggs, larvae, and adults—breaking the flea cycle with easy, premeasured topical application tubes. Ideal for indoor and outdoor cats, this 4-dose pack ensures hassle-free monthly protection without prescriptions.













| ASIN | B004QN0MJQ |
| Active Ingredients | Imidacloprid, Pyriproxyfen |
| Age Range Description | Adult |
| Brand | Advantage |
| Brand Name | Advantage |
| Customer Reviews | 4.5 out of 5 stars 13,635 Reviews |
| Dog Breed Size | Large |
| Global Trade Identification Number | 00724089202246 |
| Item Form | Topical |
| Item Weight | 23 g |
| Item form | Topical |
| Item volume | 3.2 Milliliters |
| Item weight | 23 g |
| Manufacturer | Bayer |
| Manufacturer Part Number | 81520224 |
| Model Number | 86336790 |
| Scent | fragrance_free |
| Scent Name | fragrance_free |
| Target Species | Cat |
| UPC | 727516696311 724089378774 643996929094 724089616852 724089202246 024089616853 788995790068 891962001323 |
| Unit Count | 4 Count |
| Volume | 3.2 Milliliters |
D**N
Works fast and keeps the fleas away!
I use Advantage II Large Cat (for cats over 9 lbs) on my big boy and it’s been excellent. Within about 12 hours of applying it I started seeing dead fleas, and after a full application the problem was under control. It kills adults, larvae, and eggs, so it actually breaks the cycle instead of just treating what’s visible. Application is easy just part the fur at the base of the neck and apply. No strong smell, and once it’s dry it’s waterproof. He’s over 9 lbs so this size is perfect for him, and I’ve had no irritation or issues. Reliable, vet-recommended, and effective. Highly recommend for large cats if you’re dealing with fleas or want solid monthly prevention!
J**A
It worked very well for my cats!
I have two indoor cats that had never had fleas before. After a trip, we noticed they were scratching a lot. I wasn’t sure the first product had completely solved the problem, so I tried Advantage II. I applied it to both cats on the same day. The next day, I found several fleas around the house, especially near their favorite sleeping area. The fleas were large, but they were lying on their sides and barely moving, which showed the product was working. My cats were much more comfortable after the treatment, and the number of fleas quickly started to decrease. I’ll continue vacuuming to help break the flea cycle, but I’m very happy with the results so far. It was easy to apply and seemed to work quickly. I recommend it to anyone dealing with a similar situation, especially since sometimes you don’t see fleas on your pets — you only notice the scratching.
B**E
Fast acting, easy application.
Worked well. I have a long haired and short haired cat and had no problems with apply on either of them. I noticed dead fleas by the morning and any scratching and stopped. Great product and highly recommend.
T**I
Exactly what is described
Perfect. Worked great.
A**R
PLEASE TAKE OFF THE SHELF BAD BATCH PLEASE
I CANT BELIEVE AMAZON HASNT PULLED THIS! PLEASE BELIEVE THE REVIEWS ORDER FROM ANOTHER SITE! BAD BAD BAD BATCH!!!!! I have only used this product over the years, no other brand. I have 2 cats under 10 lbs(Billie&Koya) 1 cat that's 17 lb (Oliver). For my big boy I ordered this medication off amazon. For my two little ones I ordered off chewy. I gave each cat there application same day. (Oliver= big boy) acted funny when I applied it, like it hurt. 2 days later I noticed he's loosing hair at application site! Now 2 weeks later it's very obvious he is bald there. He has also puked several times the past 2 weeks. I would say probably 6 times, he had diarrhea too, so bad that he only made it next to the cat box. HE HAS NEVER DONE THAT! My other two kitties who had a different batch have no baldness at the application site. HOWEVER- Billie and Oliver snuggle often, and play the most with eachother. A week ago I noticed a spot on Billies ear that I thought was food. I NOW HAVE REALIZED IT WAS A CHEMICAL BURN!!! He has 2 patches of missing fur on the back of his ears, which would have touched Oliver when they snuggled. PLEASE BUY LOCALLY OR SOME PLACE ELSE! AMAZON PLEASE I BEG YOU REMOVE THIS! WE ALL LOVE OUR PETS AND KNOW WHEN SOMETHING HURTS THEM! - PLEASE NOTE- this is now over 2 weeks later, hair has started growing back. It was a LOT worse, he has very thick hair though. *when he leans his head down like eating/drinking, or crouched on all 4s it's VERY visible. I couldn't get a good pic, but will update if I can. It's about 2 inches long.
Trustpilot
2 months ago
2 weeks ago