---
product_id: 186423782
title: "- SPM Supreme - 3 Specialized Pro-Resolving Mediators from Fish Oil - Omega 3 Fatty Acids Supplement, SPM Fish Oil (60 Softgels)"
brand: "designs for health"
price: "€ 104.24"
currency: EUR
in_stock: true
reviews_count: 11
category: "Designs For Health"
url: https://www.desertcart.fr/products/186423782-spm-supreme-3-specialized-pro-resolving-mediators-from-fish-oil
store_origin: FR
region: France
---

# 150mg total pro-resolving mediators Non-GMO, gluten & dairy free 300mg active SPM concentrate - SPM Supreme - 3 Specialized Pro-Resolving Mediators from Fish Oil - Omega 3 Fatty Acids Supplement, SPM Fish Oil (60 Softgels)

**Brand:** designs for health
**Price:** € 104.24
**Availability:** ✅ In Stock

## Summary

> 🐠 Unlock your body's natural inflammation resolution—because your wellness deserves the best.

## Quick Answers

- **What is this?** - SPM Supreme - 3 Specialized Pro-Resolving Mediators from Fish Oil - Omega 3 Fatty Acids Supplement, SPM Fish Oil (60 Softgels) by designs for health
- **How much does it cost?** € 104.24 with free shipping
- **Is it available?** Yes, in stock and ready to ship
- **Where can I buy it?** [www.desertcart.fr](https://www.desertcart.fr/products/186423782-spm-supreme-3-specialized-pro-resolving-mediators-from-fish-oil)

## Best For

- designs for health enthusiasts

## Why This Product

- Trusted designs for health brand quality
- Free international shipping included
- Worldwide delivery with tracking
- 15-day hassle-free returns

## Key Features

- • **Pure & Clean Ingredients:** Non-GMO, gluten-free, and dairy-free with natural lemon to eliminate fishy aftertaste.
- • **Clinically Trusted Formula:** Top choice of functional medicine pros for effective, science-backed wellness.
- • **Optimized Absorption & Potency:** 300mg active fractionated SPM concentrate delivers maximum bioavailability per serving.
- • **Pain Relief Without Compromise:** Reduce reliance on NSAIDs with a natural, targeted omega-3 solution designed for modern health challenges.
- • **Cutting-Edge Inflammation Support:** Harness the power of 3 specialized pro-resolving mediators to naturally resolve inflammation faster.

## Overview

Designs for Health SPM Supreme delivers a potent, clinically trusted blend of 3 specialized pro-resolving mediators derived from omega-3 fish oil. Each softgel contains 300mg of active fractionated SPM concentrate standardized to 150mg total pro-resolving mediators, supporting the body's natural inflammatory response. This non-GMO, gluten- and dairy-free formula is enhanced with natural lemon to avoid fishy taste, making it a premium choice for adults seeking advanced inflammation and pain management.

## Description

Buy Designs for Health SPM Supreme - 3 Specialized Pro-Resolving Mediators from Fish Oil - Omega 3 Fatty Acids Supplement, SPM Fish Oil (60 Softgels) on desertcart.com ✓ FREE SHIPPING on qualified orders

Review: Very Effective at reducing inflammation - It is definitely expensive but it works to reduce inflammation and associated pain. I keep a bottle at home for when I have inflammation flares and take two twice a day for the first 3 days then reduce down to the normal dose. There are multiple studies showing the effectiveness of SPM’s to reduce inflammation, speed up healing and reduce pain. Good product that reduces my need to take NSAIDS such as ibuprofen.
Review: Great type of fish oil - This is a great supplement for lowering inflammation. If you need just one fish oil, this is the one.

## Features

- Targeted SPM Fish Oil - Synergistic blend of Specialized Pro-resolving Mediators (SPMs). SPMs are a class of newly discovered molecules derived from naturally-occurring omega-3 and omega-6 fatty acids.
- These three SPMs are designed to help support the body’s natural ability to respond to physical challenges and 'resolve' the initial steps in the natural inflammatory process.*
- Natural lemon and tocotrienols help avoid fishy taste.
- Pure and Powerful - Contains 300mg active fractionated SPM concentrate standardized to 150mg Total Pro-Resolving Mediators. This product is Non-GMO and contains No Gluten or Dairy.
- Clinically-Trusted Care - DFH is the #1 practitioner supplement brand recommended by functional medicine professionals and the #1 practitioner supplement brand personally trusted by functional medicine professionals.**

## Technical Specifications

| Specification | Value |
|---------------|-------|
| ASIN | B084HJW58N |
| Age Range Description | Adult |
| Allergen Information | Fish, Gluten Free |
| Best Sellers Rank | #30,077 in Health & Household ( See Top 100 in Health & Household ) #81 in Fish Oil Nutritional Supplements |
| Brand | Designs for Health |
| Brand Name | Designs for Health |
| Container Type | Bottle |
| Customer Reviews | 4.6 out of 5 stars 258 Reviews |
| Diet Type | Gluten Free |
| Dosage Form | Softgel |
| Flavor | Unflavored |
| Item Form | Softgel |
| Item Weight | 5.6 Ounces |
| Manufacturer | Designs for Health |
| Material Features | Gluten Free |
| Material Type Free | Dairy Free, GMO Free |
| Number of Items | 1 |
| Primary Supplement Type | Active Fractionated Marine Lipid Concentrate |
| Product Benefits | Supports a normal inflammatory response* |
| Special Ingredients | Active Fractionated Marine Lipid Concentrate |
| UPC | 879452005518 |
| Unit Count | 60.0 Count |

## Product Details

- **Age Range (Description):** Adult
- **Brand:** Designs for Health
- **Diet Type:** Gluten Free
- **Flavor:** Unflavored
- **Item Form:** Softgel
- **Item Weight:** 5.6 Ounces
- **Primary Supplement Type:** Active Fractionated Marine Lipid Concentrate
- **Product Benefits:** Supports a normal inflammatory response*
- **Special Ingredients:** Active Fractionated Marine Lipid Concentrate
- **Unit Count:** 60.0 Count

## Images

![- SPM Supreme - 3 Specialized Pro-Resolving Mediators from Fish Oil - Omega 3 Fatty Acids Supplement, SPM Fish Oil (60 Softgels) - Image 1](https://m.media-amazon.com/images/I/71ly+umv7KL.jpg)

## Questions & Answers

**Q: Is this product third party tested?**
A: SPM is great  I was out of it for 2 months and all my bones went awful.  started again and feel mu

**Q: What country manufactures these?**
A: I'm pretty sure made in US. Suggested

**Q: How big are the softgels? Are they easy to swallow?**
A: They are easy to swallow, not big.

## Customer Reviews

### ⭐⭐⭐⭐⭐ Very Effective at reducing inflammation
*by J***E on September 21, 2025*

It is definitely expensive but it works to reduce inflammation and associated pain. I keep a bottle at home for when I have inflammation flares and take two twice a day for the first 3 days then reduce down to the normal dose. There are multiple studies showing the effectiveness of SPM’s to reduce inflammation, speed up healing and reduce pain. Good product that reduces my need to take NSAIDS such as ibuprofen.

### ⭐⭐⭐⭐⭐ Great type of fish oil
*by S***Y on December 8, 2025*

This is a great supplement for lowering inflammation. If you need just one fish oil, this is the one.

### ⭐⭐⭐⭐⭐ Great Product!
*by A***D on February 11, 2026*

I have taken ibuprofen lots of days for joint pain. Since taking this product, about 6 weeks now I have not had to take one! I have had a Tylenol for a mild headache, but that’s all. This product is amazing!

## Frequently Bought Together

- Designs for Health SPM Supreme - 3 Specialized Pro-Resolving Mediators from Fish Oil - Omega 3 Fatty Acids Supplement, SPM Fish Oil (60 Softgels)
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*Product available on Desertcart France*
*Store origin: FR*
*Last updated: 2026-03-01*