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🛡️ Protect your pup like a pro—because your dog deserves the best defense!
FRONTLINE Plus Flea and Tick Treatment for Medium Dogs (23-44 lbs) delivers fast-acting, waterproof protection that kills fleas, flea eggs, larvae, chewing lice, and ticks for a full 30 days with just one monthly topical dose. Trusted by pet owners for over 20 years, its dual active ingredients (fipronil and (S)-methoprene) break the flea life cycle while providing safe, easy application suitable for puppies 8 weeks and older. Keep your dog pest-free and protected year-round with this veterinarian-recommended solution.

















| ASIN | B07NGRSVLF |
| ASIN | B07NGRSVLF |
| Active Ingredients | fipronil and (S)-methoprene |
| Age Range Description | All Life Stages |
| Allergen Information | Gluten Free |
| Best Sellers Rank | #299 in Pet Supplies ( See Top 100 in Pet Supplies ) #6 in Dog Flea Drops |
| Brand Name | Frontline |
| Customer Reviews | 4.4 4.4 out of 5 stars (23,817) |
| Date First Available | February 7, 2019 |
| Dog Breed Size | Medium |
| Included Components | Applicator |
| Item Form | Liquid |
| Item Type Name | Flea and Tick Treatment for Dogs Medium Dogs |
| Item model number | 72218 |
| Manufacturer | Boehringer Ingelheim Animal Health |
| Manufacturer | Boehringer Ingelheim Animal Health |
| Manufacturer Part Number | 65331-5 |
| Manufacturer recommended age | 1 month and up |
| Model Number | 72218 |
| Product Dimensions | 0.63 x 5.75 x 4.5 inches; 2.08 ounces |
| Scent Name | Unscented |
| Target Species | Medium Dog, 23-44 Pounds |
| UPC | 611030624557 350604062455 |
| Unit Count | 8 Count |
| Volume | 6 Milliliters |
| Warranty Description | If you are not satisfied with Frontline Plus for any reason, please contact the Boehringer-Ingelheim Animal Health Customer Care Team at: 1-800-660-1842. |
B**T
Gets rid of pests
FRONTLINE Plus has been very effective at keeping fleas and ticks under control. It’s easy to apply, doesn’t have a strong odor, and hasn’t caused any irritation. I like that it provides long lasting protection with just one monthly dose. This has been a reliable product for us and definitely worth the purchase. Your pets will be happy you bought it.
M**R
Great product and service.
We loved this product. We were on the automatic ship plan and that was nice. We would recommend this dealer to anyone. We stopped because our dog was hit by a car.
B**A
Excellent product, BUT...
This is an excleent product, but it is not a miracle worker. In other words, you need to use the stuff properly. (1) this product is water resistant...not soap resistant. So if you use this stuff then go and use some of that heavily perfumes soapy shampoo that msot people use..then you are washign it right off. (2) if you chose to bathe your dog..bathe him/her first then wait 2-3 days THEN apply the product so that it will be distrubited properly. (3) Remember that if you have a heavy flea problem that you need to treat the pet and the environment. You can't jsut put it on the dog and not get rid of the fleas in your house, car, yard, etc.. Yeah it will kill the fleas on him/her, but they will get reinfested with fleas everytime they go back into the flea filled environment. This is the only product that I use for my dog. Of you purchase ANYTHING over the counter (biospot, hartz ::shudders::, etc) then you are wasting your money. Flea dips work, but they only kill the fleas that are on the dog when you bathe him/her. Frontline PLUS is great becasue it keeps killing for up to a month. Also, Frontline Plus has a better range of killing fleas than plain ole' Frontline. The "PLUS" means that it kills larvae and eggs and so much more than adult fleas. IF USED CORRECTLY and ROUTINELY this is an EXCELLENT product!!! I highly recommend it. This product also kills ticks.
�**�
Verdict is still out
I can’t say too much about this product yet because I just ordered it but before you order it make sure it’s what you want because you cannot return this product. I was going to return it and get something different because after I ordered it, the vet recommended that we get something different because this seems to not deter the fleas as well as the ingredients used to work. We have put it on the dog and she has been fine since then. When I see how the flea and tick problems go or don’t go, hopefully, I will update.
I**S
Flea collar
Will buy again
J**M
Works
Works every year
T**Z
Doesn’t work in March in San Antonio TX at all!!
Not working so well. Have been using on the absolute reg and dog still getting ticks. They don’t die either!! She also gets the oral stuff regularly and I spray the yard! What the heck!! I also spray her bedding etc w the natural stuff and her as well. Really the natural spray is the only decent stuff but can’t spray her constantly. Do spray bedding twice a day. Any suggestions will be appreciated. No one wants to see a pic of ticks. 😬😵💫
G**S
Good price!
Best brand for flea and tick! Tried another well known brand and it made my dog itch terribly. Went back to Frontline and never looked back. This is good stuff! Have bought this from Amazon many times.
D**L
It says 6-doses but what arrived was only the 3-dose pack.
Trustpilot
2 months ago
4 days ago